RNA in health & disease

Kalsotra Lab is looking for new postdoctoral scientists to join the lab. For more information check our job posting here.

Recent lab News

Sandip Chorghade is promoted to the rank of Visiting Research Scientist, Congrats and well-deserved Sandip!

Muscular Dystrophy Association funds Kalsotra Lab to study mechanisms of fatty liver disease and impaired drug metabolism in DM1. Congrats to Zac Dewald and the whole team!!!

Our collaborative work with W. Yokoyama lab at Wash U is accepted by J Exp Med. Congrats to Sushant (co-first author) for a job well done!

Jessica and Nash’s review on the discovery, function and regulation of ESRP proteins was published in Biochem Soc Trans. Way to Go Jess!

Ullas was awarded the 2023 Biochemistry Trust of Urbana Award for demonstrating excellence in graduate studies and research. Well done and Congratulations Ullas!!

Subhashis was awarded the Michael A. Recny Graduate Fellowship in Biochemistry!! Way to go!!

Jeongmin Lee was awarded the Outstanding Undergraduate Thesis Award in Biochemistry with highest distinction, Congratulations Jeongmin!.

An absolute honor to hood my student Ullas Chembazhi at the SMCB graduation ceremony. Congrats Dr. Chembazhi.

Jessica Derham and Subhashis Natua passed their Ph.D. qualifying exams with flying colors. Heartiest congratulations to both!

Best wishes to Ullas for starting his postdoc in the Morrissey lab at U Penn.

Ishita Purwar won the 2023 School of MCB Summer Undergraduate Research Fellowship. Well done Ishita!

Ullas Chembazhi gave a talk about the lab’s recent findings on dysregulation of RNA splicing in alcoholic liver disease at the Gordon Conference in Ventura, CA!! Way to go Ullas!

Subhashis presented a poster on post-transcriptional gene regulation in the heart and wowed everyone at the Keystone Symposia in Santa Fe, NM. Nicely done!!

Our collaborative manuscript with Wenyan Mei’s group examining PTBP1’s role in intestinal epithelial regeneration is published in NAR. Congrats to Ullas!!

Waqar’s manuscript examining SRSF1’s role in the liver is published in Nature Communications. Congrats to the whole team!!

Graduate students Adesanya Oluwafolajimi and Diptatanu Das join the Kalsotra Lab! Welcome to the party ‘Fola and Dipta!! 

Ullas successfully defended his thesis and accepted a postdoc in the Morrissey lab at U Penn. Well done Dr. Chembazhi!!


Splicing factor SRSF1 deficiency in the liver triggers NASH-like pathology and cell death

This work was published in Nature Communications.

Cellular plasticity balances the metabolic and proliferation dynamics of a regenerating liver

This work was published in Genome Research.

Non-muscle RBFOX2 triggers cardiac conduction defects in myotonic dystrophy

This work was published in Developmental Cell.

ESRP2 regulates the Hippo pathway to aid liver regeneration

This work was published in Nature Structural & Molecular Biology.

Poly(A) tail length regulates PABPC1 to tune translation in the heart

This work was published in eLife.

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Meet the crew

The people who keep the science going!! We are a fun bunch of scientists, who love to work hard and party harder!!